Journal article
Reticular Pseudodrusen on the Risk of Progression in Intermediate Age-Related Macular Degeneration
Z Wu, H Kumar, LAB Hodgson, RH Guymer
American Journal of Ophthalmology | ELSEVIER SCIENCE INC | Published : 2022
Abstract
PURPOSE: To examine the association between reticular pseudodrusen (RPD) and progression to late age-related macular degeneration (AMD) in individuals with intermediate AMD. DESIGN: Prospective cohort study. METHODS: Two hundred eighty eyes from 140 participants with bilateral large drusen underwent multimodal imaging (MMI), including optical coherence tomography (OCT), near-infrared reflectance (NIR), fundus autofluorescence, and color fundus photography (CFP), at 6-monthly intervals up over a 36-month follow-up period. The presence of RPD per eye was determined based on either a combined MMI criterion, or each individual imaging modality, and their extent measured on combined OCT and NIR i..
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Awarded by Bayer
Funding Acknowledgements
Funding Support: This study was supported by the National Health & Medical Research Council of Australia (grants APP1181010 [R.H.G., Z.W.] and APP1138253 [R.H.G.] , and fellowship GNT1103013 [R.H.G.] and #2008382 [Z.W.] ) and a Macular Disease Foundation Australia grant (Z.W., R.H.G.) . The Centre for Eye Research Australia (CERA) receives operational infrastructure support from the Victorian Government. The funders had no role in the manuscript writing and the decision to submit the manuscript for publication.